TAL effector

TAL effector

Auto-curated
Playing 1/13
  • Tal effector bound to DNA

    YouTube 00:09
  • TAL Effector + DNA binding complex structure (PDB 3UGM)

    YouTube 00:24
  • Transcription activator-like effector nucleases (TALENs)

    YouTube 03:19
  • Construction of a 10 RVDs TALEN array by Golden Gate cloning system

    YouTube 00:42
  • TALEN: a target specific DNA editing tool.

    YouTube 03:29
  • Why We Chose HIV and CCR5 First

    YouTube 03:00
  • Growing Tomato Plant From Tomato Slice Time Lapse

    YouTube 04:12
  • What is Genetic Engineering?

    YouTube 02:33
  • penelope scott // rät (lyrics)

    YouTube 03:15
  • Genome Editing with engineered nucleases

    YouTube 02:17
  • Gene Therapy Basics

    YouTube 03:30
  • محفز هرمون السعادة و النوم - الحمض الأميني تريبتوفان

    YouTube 02:42
  • A brief introduction to C. elegans

    YouTube 02:12

TAL effectors are proteins secreted by Xanthomonas bacteria via their type III secretion system when they infect various plant species. These proteins can bind promoter sequences in the host plant and activate the expression of plant genes that aid bacterial infection. They recognize plant DNA sequences through a central repeat domain consisting of a variable number of ~34 amino acid repeats. There appears to be a one-to-one correspondence between the identity of two critical amino acids in each repeat and each DNA base in the target sequence. These proteins are interesting to researchers both for their role in disease of important crop species and the relative ease of retargeting them to bind new DNA sequences. Similar proteins can be found in the pathogenic bacterium Ralstonia solanacearum and Burkholderia rhizoxinica, as well as yet unidentified marine microorganisms. The term TALE-likes is used to refer to the putative protein family encompassing the TALEs and these related proteins.

Discover in context

This site is not available in the landscape mode.
Please rotate your phone or install our app.